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Aerobic {Mo 72 V 30 } nanocluster‐catalysed heterogeneous one‐pot tandem synthesis of benzimidazoles
Author(s) -
Khoshyan Ashkan,
Pourtahmasb Mehrdad,
Feizpour Fahimeh,
Jafarpour Maasoumeh,
Rezaeifard Abdolreza
Publication year - 2019
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4638
Subject(s) - chemistry , polyoxometalate , tandem , catalysis , leaching (pedology) , combinatorial chemistry , dehydrogenation , one pot synthesis , organic chemistry , materials science , environmental science , soil science , composite material , soil water
A novel heterogeneous one‐pot protocol is developed for tandem aerobic synthesis of benzimidazoles through dehydrogenative coupling of primary benzylic alcohols and aromatic diamines co‐catalysed by Keplerate‐type {Mo 72 V 30 } polyoxometalate and N ‐hydroxyphthalimide (NHPI). The catalytic system also works well for the synthesis of benzimidazoles using benzaldehydes, as commonly used starting materials, in the absence of NHPI. The high activity of the solid nanocluster provides standard conditions avoiding current limitations of oxidation methods including high catalyst loadings. The spectral results and leaching experiments revealed that the nanocapsule preserved its structural integrity after being reused in consecutive runs.