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Isatin‐SO 3 H coated on amino propyl modified magnetic nanoparticles (Fe 3 O 4 @APTES@isatin‐SO 3 H) as a recyclable magnetic nanoparticle for the simple and rapid synthesis of pyrano[2,3‐d] pyrimidines derivatives
Author(s) -
Sajjadifar Sami,
Gheisarzadeh Zohreh
Publication year - 2019
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4602
Subject(s) - isatin , malononitrile , chemistry , yield (engineering) , magnetic nanoparticles , nuclear chemistry , solvent , nanoparticle , catalysis , organic chemistry , nanotechnology , materials science , metallurgy
Isatin‐SO 3 H coated on amino propyl modified magnetic nanoparticles (Fe 3 O 4 @APTES@isatin‐SO 3 H) is found to be a novel, efficient, and reusable magnetic nanocatalyst, and characterized by FT‐IR, SEM, TEM, XRD, EDX, VSM, and TGA analysis. The magnetic nanocatalyst demonstrated outstanding performance in synthesis of pyrano[2,3‐d] pyrimidines derivatives via one‐pot three‐component reaction of various aromatic aldehydes 1, malononitrile 2, and barbituric acid 3 under reflux conditions in mixture of H 2 O:EtOH (1:1) as solvent. Easy workup procedure, short reaction time, high yield, simple preparation and easy recovery of the catalyst, mild reaction conditions are some advantages of this work.