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Synthesis of quinazolines over recyclable Fe 3 O 4 @SiO 2 ‐PrNH 2 ‐Fe 3+ nanoparticles: A green, efficient, and solvent‐free protocol
Author(s) -
Eidi Esmaiel,
Kassaee Mohamad Z.,
Nasresfahani Zahra,
Cummings Peter T.
Publication year - 2018
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4573
Subject(s) - thermogravimetric analysis , chemistry , fourier transform infrared spectroscopy , catalysis , nuclear chemistry , transmission electron microscopy , ammonium acetate , green chemistry , scanning electron microscope , aldehyde , nanoparticle , solvent , condensation reaction , chemical engineering , analytical chemistry (journal) , inorganic chemistry , nanotechnology , organic chemistry , reaction mechanism , materials science , high performance liquid chromatography , engineering , composite material
A practical and efficient method is developed for efficient synthesis of quinazoline derivatives through condensation reaction of 2‐aminoaryl ketone, an aldehyde, and ammonium acetate, over magnetic Fe 3 O 4 @SiO 2 ‐PrNH 2 ‐Fe 3+ NPs as a recyclable nanocatalyst, under solvent‐free conditions. The as‐prepared nanocatalyst was characterized using Fourier transform infrared spectroscopy (FT‐IR), X‐ray diffraction (XRD), field emission scanning electron microscopy (FE‐SEM), transmission electron microscopy (TEM), thermogravimetric analysis (TGA), and vibrating sample magnetometer (VSM). Mild conditions, easy work up, high purity of the products, recyclability, readily availability, nontoxicity, economical, and environmental‐friendly nature of the iron catalyst are the attractive features of this methodology.