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Denitrogenative Pd/Cu‐catalyzed Suzuki‐type Cross‐coupling of Aryltrifluoroborates with Arylhydrazine Hydrochlorides in Water under Room Temperature
Author(s) -
Wang Guofang,
Meng Mengting,
Deng Liping,
Cheng Kai,
Qi Chenze
Publication year - 2018
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4203
Subject(s) - chemistry , catalysis , palladium , ligand (biochemistry) , suzuki reaction , nitrogen , polymer chemistry , coupling (piping) , water soluble , coupling reaction , organic chemistry , combinatorial chemistry , metallurgy , receptor , materials science , biochemistry
A water‐soluble palladium‐catalyzed Suzuki‐type cross‐coupling of aryltrifluoroborates with arylhydrazide hydrochlorides was efficiently developed under mild and environmentally benign conditions, in water without any ligand. The newly developed Pd/Cu co‐catalyzed denitrogenative reaction gave a range of structurally diverse substituted biaryls with good to excellent yields, in which the byproduct was nitrogen.