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Highly efficient Pd‐PEPPSI‐IPr catalyst for N ‐(4‐pyridazinyl)‐bridged bicyclic sulfonamides via Suzuki–Miyaura coupling reaction
Author(s) -
Sura Mallikarjuna Reddy,
Bijivemula N. Reddy,
Pogula Sreekanth Reddy,
Motakatla Venkata Krishna Reddy,
Madhvesh Pathak,
Peddiahgari Vasu Govardhana Reddy
Publication year - 2018
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.4068
Subject(s) - chemistry , catalysis , aryl , suzuki reaction , bicyclic molecule , coupling reaction , coupling (piping) , combinatorial chemistry , organic chemistry , palladium , medicinal chemistry , metallurgy , alkyl , materials science
A protocol for the Suzuki–Miyaura coupling of novel 2‐(6‐chloropyridazin‐3‐yl)‐5‐(aryl/heteroarylsulfonyl)‐2,5‐diazabicyclo[2.2.1]heptanes and heteroarylboronic acids to afford variety of coupled products was realized. Pd‐PEPPSI‐IPr catalyst was found to be a powerful and reusable catalyst under relatively mild reaction conditions.