In vitro  antitumour activity of some organogermanium radioprotectors | Zendy

Célariès Benoît | Zendy; Gielen Marcel | Zendy; de Vos Dick | Zendy; Rima Ghassoub | Zendy

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In vitro antitumour activity of some organogermanium radioprotectors

Author(s) -

Célariès Benoît,

Gielen Marcel,

de Vos Dick,

Rima Ghassoub

Publication year - 2003

Publication title -

applied organometallic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.53

H-Index - 71

eISSN - 1099-0739

pISSN - 0268-2605

DOI - 10.1002/aoc.403

Subject(s) - chemistry , etoposide , in vitro , elemental analysis , nuclear magnetic resonance spectroscopy , germanium , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , biochemistry , silicon , chemotherapy , medicine , surgery

Four germanium derivatives of 2,2′‐oxydiethanethiol and 2,2′‐thiodiethanethiol have been synthesized and characterized by 1 H and 13 C NMR, mass spectroscopy and elemental analysis. The antitumour activity of one of them is comparable to those of cis ‐platin and etoposide. Copyright © 2003 John Wiley & Sons, Ltd.

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