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Bis‐benzimidazolium‐palladium system catalyzed Suzuki‐Miyaura coupling reaction of aryl bromides under mild conditions
Author(s) -
Lin YiRang,
Chiu ChienCheng,
Chiu HuaiTsu,
Lee DongSheng,
Lu TaJung
Publication year - 2018
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3896
Subject(s) - chemistry , aryl , palladium , catalysis , coupling reaction , aqueous medium , compatibility (geochemistry) , reaction conditions , combinatorial chemistry , organic chemistry , polymer chemistry , aqueous solution , chemical engineering , alkyl , engineering
Bis‐benzimidazolium salts were prepared successfully from commercially available and inexpensive o ‐phenylenediamine through a series of simple reactions. The bis‐NHC‐Pd complexes prepared in situ can catalyze Suzuki‐Miyaura cross‐coupling reaction under very mild conditions in aqueous media with excellent yields. The efficiency of this reaction is demonstrated by its compatibility with a range of functional groups. Di‐ ortho ‐substituted biaryls could be accomplished in 89–99% yields. Moreover, the rigorous exclusion of air or moisture is not required in these transformations.