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A new azo‐Schiff base: Synthesis, characterization, biological activity and theoretical studies of its complexes
Author(s) -
Al Zoubi Wail,
AlHamdani Abbas Ali Salih,
Ahmed Susan Duraid,
Ko Young Gun
Publication year - 2018
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3895
Subject(s) - chemistry , schiff base , molar conductivity , ligand (biochemistry) , benzoic acid , metal , metal ions in aqueous solution , nuclear chemistry , proton nmr , inorganic chemistry , polymer chemistry , stereochemistry , organic chemistry , biochemistry , receptor
A new Azo‐Schiff base ligand L was prepared by reaction of m‐hydroxy benzoic acid with (Schiff base B) of 3‐[2‐(1H–indol‐3‐yl)‐ethylimino]‐1.5‐dimethyl‐2‐phenyl‐2,3‐dihydro‐1H‐pyrazol‐4‐ylamine. This synthesized ligand was used for complexation with different metal ions like Ni(II), Co(II), Pd(II) and Pt(IV) by using a molar ratio of ligand: metal as 1:1. Resulted compounds were characterized by NMR ( 1 H and 13 C), UV–vis spectroscopy, TGA, FT‐IR, MS, elemental analysis, magnetic moment and molar conductivity studies. The activation thermodynamic parameters, such as ΔE*, ΔH * , ΔS * , ΔG * and K are calculated from the TGA curves using Coats ‐ Redfern method. Hyper Chem‐8 program has been used to predict structural geometries of compounds in gas phase. The biological activities of Schiff base and its complexes had been tested in vitro against, two Gram positive bacteria ( Bacillus subtillis and Staphylococcus aureus ) and two Gram negative bacteria ( Escherichia coli and Pseudomonas aeruguinosa ).