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Synthesis of pyrano[2,3‐ c ]pyrazole derivatives using Fe 3 O 4 @SiO 2 @piperidinium benzene‐1,3‐disulfonate (Fe 3 O 4 @SiO 2 nanoparticle‐supported IL) as a novel, green and heterogeneous catalyst
Author(s) -
GhorbaniVaghei Ramin,
Mahmoodi Jafar,
Shahriari Azadeh,
Maghbooli Yaser
Publication year - 2017
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3816
Subject(s) - chemistry , malononitrile , ethyl acetoacetate , hydrazine (antidepressant) , pyrazole , hydrate , yield (engineering) , benzene , catalysis , aryl , nuclear chemistry , medicinal chemistry , organic chemistry , materials science , alkyl , chromatography , metallurgy
A simple, green and efficient protocol for the one‐pot four‐component synthesis of pyrano[2,3‐ c ]pyrazole derivatives produced from reaction between aryl aldehydes, ethyl acetoacetate, malononitrile and hydrazine hydrate in the presence of nano magnetic piperidinium benzene‐1,3‐disulfonate was synthesized in water at 60 °C. The Fe 3 O 4 @SiO 2 nanoparticle‐supported IL was designed and synthesized. The present process offers advantages such as clean reaction, short reaction time, good to excellent yield, easy purification and easy recoverable catalyst.