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Nanomagnetically modified thioglycolic acid (γ‐Fe 2 O 3 @SiO 2 ‐SCH 2 CO 2 H): Efficient and reusable green catalyst for the one‐pot domino synthesis of spiro[benzo[ a ]benzo[6,7]chromeno[2,3‐ c ]phenazine] and benzo[ a ]benzo[6,7]chromeno[2,3‐ c ]phenazines
Author(s) -
Abbasi Pour Sajjad,
YazdaniElahAbadi Afshin,
Afradi Mojgan
Publication year - 2017
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3791
Subject(s) - chemistry , thioglycolic acid , catalysis , isatin , knoevenagel condensation , nuclear chemistry , heterogeneous catalysis , organic chemistry , medicinal chemistry
Superparamagnetic nanoparticles of modified thioglycolic acid (γ‐Fe 2 O 3 @SiO 2 ‐SCH 2 CO 2 H) represent a new, efficient and green catalyst for the one‐pot synthesis of novel spiro[benzo[ a ]benzo[6,7]chromeno[2,3‐ c ]phenazine] derivatives via domino Knoevenagel–Michael–cyclization reaction of 2‐hydroxynaphthalene‐1,4‐dione, benzene‐1,2‐diamines, ninhydrin and isatin. This novel magnetic organocatalyst was easily isolated from the reaction mixture by magnetic decantation using an external magnet and reused at least six times without significant loss in its activity. The catalyst was fully characterized using various techniques. This procedure was also applied successfully for the synthesis of benzo[ a ]benzo[6,7]chromeno[2,3‐ c ]phenazines.