Premium
Review: Quantitative structure–activity/property relationships as related to organotin chemistry
Author(s) -
Eng George
Publication year - 2017
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3712
Subject(s) - quantitative structure–activity relationship , chemistry , molecular descriptor , quantum chemical , computational chemistry , biochemical engineering , biological system , molecule , organic chemistry , stereochemistry , engineering , biology
The aim of this review is to examine the current status of quantitative structure–activity/property relationships (QSAR/QSPR) as related to organotin chemistry. QSAR/QSPR are mathematical models that relate some measurable biological activity or physical property in a series of similar compounds to a descriptor or descriptors associated with the molecules. Descriptors used in QSAR/QSPR studies are endless, from traditional parameters to newly developed ones. They range from quantum chemical descriptors to physicochemical parameters while QSAR/QSPR studies range from predicting bio‐toxicity of various species to estimating chromatographic parameters. The intent of the review is to provide investigators with the current state of knowledge and trends in this area.