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Polystyrene‐supported Pd(II) complex‐catalysed carboacylation of 2‐arylpyridines with alcohols via C─H bond activation under solvent‐free conditions
Author(s) -
Perumgani Pullaiah C.,
Parvathaneni Sai Prathima,
Keesara Srinivas,
Mandapati Mohan Rao
Publication year - 2017
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3581
Subject(s) - chemistry , catalysis , polystyrene , acylation , polymer chemistry , solvent , aryl , organic chemistry , coupling reaction , medicinal chemistry , combinatorial chemistry , alkyl , polymer
Polystyrene‐supported N , N ‐dimethylethylenediamine Pd(II) complex C was used as an efficient catalyst for the synthesis of aromatic ketones via ortho ‐acylation of sp 2 C─H bonds of 2‐arylpyridines with alcohols as effective coupling partners. The alcohols were oxidized with tert ‐butyl hydroperoxide to their corresponding aldehydes in situ and efficiently coupled with 2‐arylpyridines to form aryl ketones under solvent‐free conditions. Furthermore, catalyst C could be easily recovered by simple filtration and reused for five cycles without any significant decrease in its activity.