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Desulfonative pd‐catalyzed coupling of aryl trifluoroborates with arylsulfonyl chlorides
Author(s) -
Wei Zhen,
Xue Dazhong,
Zhang Haisheng,
Guan Jinyu
Publication year - 2016
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3504
Subject(s) - chemistry , aryl , catalysis , cleavage (geology) , combinatorial chemistry , bond cleavage , coupling (piping) , coupling reaction , medicinal chemistry , organic chemistry , mechanical engineering , alkyl , geotechnical engineering , fracture (geology) , engineering
A Pd‐catalyzed cross‐coupling of aryl trifluoroborates with arylsulfonyl chlorides has been successfully achieved. This transformation is a new method for the Suzuki–Miyaura‐type reaction of aryl trifluoroborates via the cleavage of C S bond, thus providing an alternative synthesis of biaryls. The reported cross‐coupling reactions are tolerant to many common functional groups regardless of electron‐donating or electron‐withdrawing nature, making these transformations attractive alternatives to the traditional Suzuki–Miyaura coupling approaches. Copyright © 2016 John Wiley & Sons, Ltd.