Premium
Synthesis, characterization and first application of chiral C 2 ‐symmetric bis(phosphinite)–Pd(II) complexes as catalysts in asymmetric intermolecular Heck reactions
Author(s) -
Karakaş Duygu Elma,
Durap Feyyaz,
Aydemir Murat,
Baysal Akın
Publication year - 2016
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3416
Subject(s) - phosphinite , chemistry , iodobenzene , trifluoromethanesulfonate , palladium , heck reaction , catalysis , intermolecular force , aryl , medicinal chemistry , organic chemistry , molecule , alkyl
A series of new chiral C 2 ‐symmetric bis(phosphinite) ligands and their palladium(II) complexes have been synthesized and for the first time used as catalysts in the palladium‐catalysed asymmetric intermolecular Heck coupling reactions of 2,3‐dihydrofuran with iodobenzene or aryl triflate. Under optimized conditions, products were obtained with high conversions and moderate to good enantioselectivities . The new C 2 ‐symmetric bis(phosphinite) ligands and their palladium(II) complexes were characterized using multinuclear NMR and Fourier transform infrared spectroscopies and elemental analysis. Copyright © 2015 John Wiley & Sons, Ltd.