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Immobilized copper(II) on nitrogen‐rich polymer‐entrapped Fe 3 O 4 nanoparticles: a highly loaded and magnetically recoverable catalyst for aqueous click chemistry
Author(s) -
Zohreh Nasrin,
Hosseini Seyed Hassan,
Pourjavadi Ali,
Bennett Craig
Publication year - 2016
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3398
Subject(s) - chemistry , catalysis , copper , click chemistry , alkyne , alkyl , azide , aqueous solution , polymer chemistry , bromide , sodium azide , aryl , nanoparticle , magnetic nanoparticles , halide , thermal stability , inorganic chemistry , nuclear chemistry , organic chemistry , chemical engineering , engineering
A heterogeneous magnetic copper catalyst was prepared via anchoring of copper sulfate onto multi‐layered poly(2‐dimethylaminoethyl acrylamide)‐coated magnetic nanoparticles and was characterized using various techniques. The catalyst was found to be active, effective and selective for one‐pot three‐component reaction of alkyl halide, sodium azide and alkyne, known as copper‐catalyzed click synthesis of 1,2,3‐triazoles. As little as 0.3 mol% of catalyst was found to be effective under the optimum conditions. The catalyst could also be recycled and reused up to seven times without significant loss of activity. Thermal stability , high loading level of copper on catalyst, broad diversity of alkyl/benzyl/allyl bromide/chloride and alkyl/aryl terminal alkynes without isolation of azide intermediate , and good to excellent yields of products make this procedure highly economical. Copyright © 2015 John Wiley & Sons, Ltd.