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Palladium complex containing two sterically hindered ligands as highly efficient catalyst for Suzuki–Miyaura reaction
Author(s) -
Shahnaz Nasifa,
Das Pankaj
Publication year - 2015
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3376
Subject(s) - chemistry , steric effects , aryl , halide , palladium , catalysis , aryl halide , coupling reaction , polymer chemistry , dimethylformamide , organic chemistry , combinatorial chemistry , medicinal chemistry , solvent , alkyl
A new palladium(II) complex containing two sterically hindered ligands, a P , P ‐bonded diphosphine and N , N ‐bonded Schiff base, within the same coordination sphere has been synthesized and investigated as a catalyst for the Suzuki–Miyaura cross‐coupling reactions of aryl halides with arylboronic acids. The reaction was highly efficient with aryl bromides in water at room temperature and aryl chlorides in dimethylformamide under relatively mild conditions. Excellent yields of coupling products were obtained for a wide range of aryl halides including heteroaryl halides with a low loading of catalyst. Copyright © 2015 John Wiley & Sons, Ltd.