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Synthesis, crystal structure, electrochemistry and antioxidative activity of copper(II), manganese(II) and nickel(II) complexes containing bis( N ‐ethylbenzimidazol‐2‐ylmethyl)aniline
Author(s) -
Wu Huilu,
Peng Hongping,
Zhang Yanhui,
Wang Fei,
Zhang Han,
Wang Cuiping,
Yang Zaihui
Publication year - 2015
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3313
Subject(s) - chemistry , molar conductivity , square pyramidal molecular geometry , trigonal bipyramidal molecular geometry , aniline , copper , nickel , manganese , ligand (biochemistry) , radical , electrochemistry , hydroxyl radical , superoxide , inorganic chemistry , coordination complex , crystal structure , coordination geometry , medicinal chemistry , electron paramagnetic resonance , transition metal , crystallography , metal , molecule , elemental analysis , organic chemistry , biochemistry , enzyme , receptor , hydrogen bond , physics , electrode , nuclear magnetic resonance , catalysis
Bis( N ‐ethylbenzimidazol‐2‐ylmethyl)aniline (Etbba) and its transition metal complexes, [Cu(Etbba)(Cl) 2 ]⋅DMF ( 1 ), [Mn(Etbba)(Cl) 2 ] ( 2 ) and [Ni(Etbba)(Cl) 2 ] ( 3 ), have been synthesized and characterized on the basis of elemental analysis, molar conductivity, UV–visible, infrared and NMR spectroscopies and X‐ray crystallography. The coordination environment of complex 1 can be described as distorted square‐based pyramidal, while complexes 2 and 3 each have a distorted trigonal bipyramidal geometry. Cyclic voltammograms of complex 1 indicate an electrochemically quasi‐reversible Cu 2+ /Cu + couple. In addition, the antioxidant activities of the free ligand and its complexes were investigated using the superoxide and hydroxyl radical scavenging methods in vitro . Complexes 1 , 2 , 3 are found to possess potent hydroxyl radical scavenging activity and to be better than standard antioxidants like vitamin C and mannitol. Furthermore, complexes 1 and 2 exhibit significant superoxide radical activity. Copyright © 2015 John Wiley & Sons, Ltd.