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Microwave‐assisted copper powder‐catalyzed coupling and cyclization of β‐bromo‐α,β‐unsaturated amides with amidine hydrochlorides leading to pyrimidinones
Author(s) -
Jiao Yang,
Cho Chan Sik
Publication year - 2015
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3301
Subject(s) - amidine , chemistry , pyrimidinones , microwave irradiation , copper , catalysis , organic chemistry , polymer chemistry , medicinal chemistry
β‐Bromo‐α,β‐unsaturated amides are coupled and cyclized with amidine hydrochlorides using microwave irradiation in the presence of a catalytic amount of copper powder and a base to give the corresponding pyrimidinones in good yields. Copyright © 2015 John Wiley & Sons, Ltd.