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Selective oxidation of benzylic, allylic and propargylic alcohols using dirhodium(II) tetraamidinate as catalyst and aqueous tert ‐butyl hydroperoxide as oxidant
Author(s) -
Wusiman Abudureheman,
Lu ChongDao
Publication year - 2015
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3281
Subject(s) - chemistry , allylic rearrangement , aqueous solution , tert butyl hydroperoxide , catalysis , medicinal chemistry , organic chemistry , alcohol oxidation
We show that the dirhodium(II) tetraamidinate complex Rh 2 (Msip) 4 efficiently catalyzes the oxidation of activated secondary alcohols at only 0.1 mol% loading. In this approach, we oxidized various benzylic, allylic and propargylic alcohols to the corresponding carbonyl compounds under mild aqueous conditions using the inexpensive oxidant T‐HYDRO® (70 wt% aqueous tert ‐butyl hydroperoxide). Copyright © 2015 John Wiley & Sons, Ltd.