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Synthesis of diaryl thioethers from aryl halides and potassium thiocyanate
Author(s) -
Hajipour Abdol R.,
Pourkaveh Raheleh,
Karimi Hirbod
Publication year - 2014
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3230
Subject(s) - chemistry , potassium thiocyanate , aryl , halide , catalysis , thiocyanate , palladium , chloride , organic chemistry , potassium , polymer chemistry , combinatorial chemistry , medicinal chemistry , alkyl
An efficient palladium catalyst was synthesized using nicotine, benzyl chloride and palladium chloride. The structure of this catalyst was characterized and it was then used for the synthesis of diaryl sufides. A variety of diaryl thioethers were synthesized under relatively mild reaction conditions. This protocol avoids foul‐smelling thiols via cross‐coupling of aryl halides with potassium thiocyanate and all substrates give the corresponding products in good to excellent yields in the presence of low amounts of the catalyst. Copyright © 2014 John Wiley & Sons, Ltd.