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Suzuki–Miyaura reactions promoted by a PdCl 2 /sulfonate‐tagged phenanthroline precatalyst in water
Author(s) -
Li Qi,
Zhang LiMing,
Bao JiaJing,
Li HongXi,
Xie JingBo,
Lang JianPing
Publication year - 2014
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3227
Subject(s) - chemistry , sulfonate , halide , catalysis , aryl , phenanthroline , medicinal chemistry , ether , extraction (chemistry) , aqueous solution , aqueous two phase system , butane , phase (matter) , organic chemistry , sodium , inorganic chemistry , nuclear chemistry , alkyl
This work reports Suzuki–Miyaura cross‐coupling reactions of arylboronic acid with aryl halide or aryl dibromide mediated by PdCl 2 (0.05 mol%) and sodium 4‐(1H‐imidazo[4,5‐f][1,10]phenanthrolin‐1‐yl)butane‐1‐sulfonate (0.05 mol%) at 100 °C in water. The corresponding cross‐coupling products were obtained in good to excellent yields. The catalytic system was recovered from the organic products by extraction with ether and the residual aqueous catalyst phase showed high activity after reuse of at least four cycles. Copyright © 2014 John Wiley & Sons, Ltd.