l ‐Proline: an efficient N,O‐bidentate ligand for copper‐catalyzed  intramolecular cyclization  reaction of 2‐iodoanilines with nitriles for the synthesis of benzimidazoles | Zendy

Yu Jiatao | Zendy; Xia Yonggen | Zendy; Lu Ming | Zendy

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l ‐Proline: an efficient N,O‐bidentate ligand for copper‐catalyzed intramolecular cyclization reaction of 2‐iodoanilines with nitriles for the synthesis of benzimidazoles

Author(s) -

Yu Jiatao,

Xia Yonggen,

Lu Ming

Publication year - 2014

Publication title -

applied organometallic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.53

H-Index - 71

eISSN - 1099-0739

pISSN - 0268-2605

DOI - 10.1002/aoc.3195

Subject(s) - chemistry , benzimidazole , intramolecular force , catalysis , ligand (biochemistry) , denticity , proline , copper , combinatorial chemistry , reaction conditions , medicinal chemistry , stereochemistry , organic chemistry , receptor , metal , amino acid , biochemistry

A novel and highly efficient copper‐catalyzed intramolecular cyclization reaction of 2‐iodoanilines with nitriles for the synthesis of benzimidazoles with l ‐proline as the ligand has been developed. A variety of substituted benzimidazole derivatives can be synthesized with high yields using this approach. Copyright © 2014 John Wiley & Sons, Ltd.

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