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Aminopropylated PEG as a novel, eco‐friendly and biodegradable basic catalyst for bis‐Michael addition to α,β‐unsaturated ketones under solvent‐free conditions
Author(s) -
Khan Tabassum,
Siddiqui Zeba N.
Publication year - 2014
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3171
Subject(s) - catalysis , chemistry , environmentally friendly , solvent , peg ratio , michael reaction , peg 400 , yield (engineering) , dispersion (optics) , organic chemistry , nuclear chemistry , chemical engineering , materials science , polyethylene glycol , metallurgy , ecology , finance , economics , biology , physics , optics , engineering
A solvent‐free and highly efficient protocol has been developed for the synthesis of novel bis‐Michael addition products ( 3a , 3b , 3c , 3d , 3e , 3f , 3g , 3h , 3i , 3j , 3k , 3l , 3m , 3n , 3o ) using aminopropylated PEG‐6000 (NH 2 ‐PEG) as a biodegradable and recyclable catalyst in excellent yields under solvent‐free conditions. Other remarkable features of this environmentally benign protocol are shorter reaction time, tolerance of a wide range of C―H‐activated acids, high yield of products, and simple experimental and work‐up procedure as compared to conventional methods. The NH 2 ‐PEG catalyst is characterized by using FT‐IR, powder XRD and scanning electron microscopy–energy dispersion X‐ray spectrometric analyses. The catalyst can be recycled several times without significant loss of its catalytic activity . Copyright © 2014 John Wiley & Sons, Ltd.