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Pd( l ‐proline) 2 complex: an efficient catalyst for Suzuki–Miyaura coupling reaction in neat water
Author(s) -
Zhang Guofu,
Luan Yuxin,
Han Xingwang,
Wang Yong,
Wen Xin,
Ding Chengrong
Publication year - 2014
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3129
Subject(s) - chemistry , catalysis , proline , combinatorial chemistry , coupling reaction , reaction conditions , organic chemistry , amino acid , biochemistry
An efficient catalytic system for Suzuki–Miyaura coupling reactions in neat water has been developed by using a water‐soluble Pd( l ‐proline) 2 catalyst. Under the optimized conditions, various biaryl compounds were obtained in good to excellent yields and a wide range of functional groups on the tested substrates were well tolerated. The catalytic system could be reused at least six times with no significant loss in its activity. Copyright © 2014 John Wiley & Sons, Ltd.