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A rapid and efficient catalysis system for the synthesis of 4‐vinylbiphenyl derivatives
Author(s) -
Ma Xiaowei,
Liu Yan,
Liu Ping,
Xie Jianwei,
Dai Bin,
Liu Zhiyong
Publication year - 2013
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3045
Subject(s) - chemistry , catalysis , toluene , base (topology) , medicinal chemistry , reaction conditions , organic chemistry , combinatorial chemistry , mathematical analysis , mathematics
A series of 4‐vinylbiphenyl derivatives were synthesized by Pd(OAc) 2 /PCy 3 ‐catalyzed Suzuki–Miyaura reaction in the presence of K 3 PO 4 .3H 2 O as base in toluene at 80°C for only 10–30 min, and the corresponding products achieved 65–98% yields. According to this efficient C―C bond‐forming method, the obtained yields of 4‐vinylbiphenyl liquid crystal compounds were up to 92–96%. Copyright © 2013 John Wiley & Sons, Ltd.