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First palladium‐catalyzed denitrated coupling reaction of nitroarenes with phenols
Author(s) -
Wang Hailei,
Yu Ajuan,
Cao Aijuan,
Chang Junbiao,
Wu Yangjie
Publication year - 2013
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.3043
Subject(s) - chemistry , catalysis , palladium , phenols , coupling reaction , reaction conditions , compatibility (geochemistry) , organic chemistry , combinatorial chemistry , chemical engineering , engineering
The first palladium‐catalyzed protocol for the denitrated coupling reaction of nitroarenes with phenols has been developed, achieving unsymmetrical diaryl ethers in moderate to excellent yields. The cyclopalladated ferrocenylimine (catalyst Ic ) exhibited highly catalytic activity for this transformation with low catalyst loading (0.75 mol%) and short reaction time (2 h). The efficiency of this reaction was demonstrated by its compatibility with a range of groups. Moreover, the rigorous exclusion of air or moisture was not required in these transformations. Copyright © 2013 John Wiley & Sons, Ltd.