CuI/amino  acid catalysis  in coupling and  cyclization  of β‐bromo‐α,β‐unsaturated carboxylic acids with terminal alkynes leading to alkylidenefuranones | Zendy

Ho Son Long | Zendy; Cho Chan Sik | Zendy; Choi HeungJin | Zendy; Sohn HoSang | Zendy

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CuI/amino acid catalysis in coupling and cyclization of β‐bromo‐α,β‐unsaturated carboxylic acids with terminal alkynes leading to alkylidenefuranones

Author(s) -

Ho Son Long,

Cho Chan Sik,

Choi HeungJin,

Sohn HoSang

Publication year - 2013

Publication title -

applied organometallic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.53

H-Index - 71

eISSN - 1099-0739

pISSN - 0268-2605

DOI - 10.1002/aoc.2963

Subject(s) - chemistry , catalysis , carboxylic acid , terminal (telecommunication) , microwave irradiation , amino acid , organic chemistry , medicinal chemistry , biochemistry , telecommunications , computer science

β‐Bromo‐α,β‐unsaturated carboxylic acids are coupled and cyclized with terminal alkynes in DMF at 110°C in the presence of a catalytic amount of CuI and amino acid along with a base to give alkylidenefuranones in good yields. Similar reaction under microwave irradiation also gave alkylidenefuranones in higher yields. Copyright © 2013 John Wiley & Sons, Ltd.

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