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Palladium‐catalyzed carbonylative cyclization of 1‐bromoallyl bromides with anilines leading to 1‐aryl‐1 H ‐pyrrol‐2(5 H )‐ones
Author(s) -
Cho Chan Sik,
Son Jong Ik,
Yoon Nam Sik
Publication year - 2012
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.2887
Subject(s) - chemistry , catalysis , palladium , carbon monoxide , aryl , carbonylation , yield (engineering) , medicinal chemistry , base (topology) , organic chemistry , polymer chemistry , mathematical analysis , alkyl , materials science , mathematics , metallurgy
1‐Bromoallyl bromides are carbonylatively cyclized with anilines under carbon monoxide pressure in DMF in the presence of a catalytic amount of a palladium catalyst along with a base to give the corresponding 1‐aryl‐1 H ‐pyrrol‐2(5 H )‐ones in moderate to good yield. Copyright © 2012 John Wiley & Sons, Ltd.