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Synthesis, physicochemical characterization and biological activity of nano complexes of iron(III) of 3(2'‐hydroxyphenyl)‐5‐(4′‐substituted phenyl) pyrazolines and aspartic acid
Author(s) -
Siddiqui Afshan,
Singh Kajal,
Singh Kanchan Lata,
Gupta Shailendra Kumar,
Ahmad Mohd Safi,
Tripathi U. N.
Publication year - 2012
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.2835
Subject(s) - chemistry , thermogravimetric analysis , deprotonation , nuclear chemistry , pyrazoline , ligand (biochemistry) , infrared spectroscopy , transmission electron microscopy , elemental analysis , crystallography , medicinal chemistry , stereochemistry , inorganic chemistry , organic chemistry , nanotechnology , materials science , receptor , ion , biochemistry
Mixed ligand complexes of Iron(III) with aspartic acid and 3(2′‐hydroxy phenyl)‐5‐(4′‐substituted phenyl) pyrazolines of type [Fe(C 4 O 4 NH 6 ) 2 (C 15 H 12 N 2 OX)] and [Fe(C 4 O 4 NH 6 )(C 15 H 12 N 2 OX) 2 ], where (C 4 O 4 NH 6 ) = aspartate, (C 15 H 12 N 2 OX) = deprotonated 3(2′‐hydroxyphenyl)‐5‐(4′‐substituted phenyl) pyrazolines (X = H, CH 3 , OCH 3 , Cl), have been synthesized. These newly synthesized derivatives have been physicochemically characterized by elemental analysis (C, H, N, Cl and Fe), magnetic moment data, thermogravimetric analysis, molar conductance, cyclic voltammetry, spectral analysis (UV–visible, IR, far IR and fast atom bombardment mass spectrometry). Scanning electron microscopy , transmission electron microscopy and X‐ray powder diffraction studies have been carried out for powdered samples, which show nanometric particles of these derivatives. Antibacterial and antifungal potential of free pyrazoline and some iron(III) complexes have been evaluated. Copyright © 2012 John Wiley & Sons, Ltd.