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CuI‐catalyzed homocoupling of terminal alkynes to 1,3‐diynes
Author(s) -
Yin Kun,
Li ChunJu,
Li Jian,
Jia XueShun
Publication year - 2011
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1681
Subject(s) - chemistry , catalysis , terminal (telecommunication) , base (topology) , combinatorial chemistry , reaction conditions , open air , medicinal chemistry , organic chemistry , mathematical analysis , telecommunications , mathematics , computer science , architectural engineering , engineering
A simple and efficient protocol for CuI‐catalyzed oxidative homocoupling reaction of terminal alkynes to symmetrical 1,4‐disubstituted 1,3‐diynes was reported. The reaction can be carried out in the open air, using NaOAc as a base in the absence of any other additives. A variety of terminal alkynes were converted to the corresponding 1.3‐diynes in good to excellent yields without any side product formation. Copyright © 2010 John Wiley & Sons, Ltd.