Organocatalytic synthesis of cyanohydrin trimethylsilyl ethers by potassium 4‐benzylpiperidinedithiocarbamate under solvent‐free conditions | Zendy

Dekamin Mohammad G. | Zendy; Alizadeh Roghieh | Zendy; Reza NaimiJamal M. | Zendy

Premium

Organocatalytic synthesis of cyanohydrin trimethylsilyl ethers by potassium 4‐benzylpiperidinedithiocarbamate under solvent‐free conditions

Author(s) -

Dekamin Mohammad G.,

Alizadeh Roghieh,

Reza NaimiJamal M.

Publication year - 2010

Publication title -

applied organometallic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.53

H-Index - 71

eISSN - 1099-0739

pISSN - 0268-2605

DOI - 10.1002/aoc.1600

Subject(s) - cyanohydrin , chemistry , trimethylsilyl cyanide , trimethylsilyl , organic chemistry , potassium cyanide , potassium , solvent , cyanide , catalysis

Potassium 4‐benzylpiperidinedithiocarbamate was found to be an efficient organocatalyst for facile addition of trimethylsilyl cyanide to a wide variety of aldehydes and ketones to afford corresponding cyanohydrin trimethylsilyl ethers in high to quantitative yields. The reaction proceeded smoothly by employing 2.0 mol% PBPDC loading under mild conditions at room temperature within a very short reaction time. Copyright © 2009 John Wiley & Sons, Ltd.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research