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2‐Pyridylquinoxaline derivatives as N , N ‐ligands for palladium‐catalyzed Suzuki–Miyaura reaction
Author(s) -
Liu Yundong,
Wu Yongwei,
Xi Chanjuan
Publication year - 2009
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1516
Subject(s) - chemistry , palladium , catalysis , aryl , yield (engineering) , toluene , molar ratio , base (topology) , organic chemistry , palladium catalyst , medicinal chemistry , polymer chemistry , alkyl , mathematical analysis , materials science , mathematics , metallurgy
The Suzuki–Miyaura reaction of aryl bromides with benzeneboronic acid catalyzed by bis(chloro)(2‐pyridylquinoxaline)palladium(II) was investigated. The scope of the bis(chloro)(2‐pyridylquinoxaline)palladium(II) was determined in toluene at 80 °C using KOH as base. Using a 0.1% molar ratio of bis(chloro)(2‐pyridylquinoxaline)palladium(II) C1 as a catalyst, aryl bromides reacted with benzeneboronic acid to afford diaryl derivatives in excellent yield. Copyright © 2009 John Wiley & Sons, Ltd.