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Preparation of novel axially chiral NHC–Pd(II) complexes and their application in oxidative kinetic resolution of secondary alcohols
Author(s) -
Liu ShiJia,
Liu Lianjun,
Shi Min
Publication year - 2009
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1491
Subject(s) - chemistry , kinetic resolution , carbene , axial symmetry , catalysis , diamine , kinetic energy , medicinal chemistry , organic chemistry , polymer chemistry , stereochemistry , enantioselective synthesis , structural engineering , engineering , physics , quantum mechanics
Novel axially chiral N ‐heterocyclic carbene (NHC) Pd(II) complexes were prepared from optically active 1,1′‐binaphthalenyl‐2,2′‐diamine (BINAM) and H 8 ‐BINAM and their crystal structures were unambiguously determined by X‐ray diffraction. These chiral N ‐heterocyclic carbene (NHC) Pd(II) complexes were applied in the oxidative kinetic resolution of secondary alcohols using molecular oxygen as a terminal oxidant or under aerobic conditions, affording the corresponding sec ‐alcohols in good yields with moderate to good enantioselectivities. Copyright © 2009 John Wiley & Sons, Ltd.