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Metal and solvent‐free cyanosilylation of carbonyl compounds with tris(pentafluorophenyl)borane
Author(s) -
Kadam Santosh T.,
Kim Sung Soo
Publication year - 2009
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1479
Subject(s) - chemistry , borane , tris , yield (engineering) , catalysis , solvent , organic chemistry , metal , medicinal chemistry , polymer chemistry , biochemistry , materials science , metallurgy
A highly effective method of the cynaosilylation of aldehydes and ketones with TMSCN in the presence of catalytic amount of B(C 6 F 5 ) 3 [tris(pentafluorophenyl)borane] has been developed. Cyano transfer from TMSCN to carbonyl group proceeds at room temperature under solvent‐free conditions. Various alehydes and ketones have been converted into the corresponding trimethylsilylether within short reaction times with excellent yield under mild conditions. Copyright © 2008 John Wiley & Sons, Ltd.