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Efficient asymmetric addition of diethylzinc to aldehydes using 3‐hydroxyazetidine derivatives as chiral ligands
Author(s) -
Liu Ruochen,
Bai Xuemei,
Zhang Zhanbin,
Zi Guofu
Publication year - 2008
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1457
Subject(s) - diethylzinc , chemistry , ethylamine , enantiomer , catalysis , enantioselective synthesis , organic chemistry , combinatorial chemistry
A new series of chiral 3‐hydroxyazetidines has been prepared from ( S )‐1‐(4‐methoxyphenyl)ethylamine. These ligands have shown excellent catalytic activities and enantiomeric selectivities in asymmetric addition of diethylzinc to aromatic aldehydes. Copyright © 2008 John Wiley & Sons, Ltd.
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