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C,N‐chelated triorganotin(IV) diesters of 4‐ketopimelic acid and their fungicidal activity
Author(s) -
Chalupa Jan,
Handlíř Karel,
Padělková Zdeňka,
Vejsová Marcela,
Buchta Vladimír,
Jirásko Robert,
Rûžička Aleš
Publication year - 2008
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1391
Subject(s) - chemistry , chelation , tin , ligand (biochemistry) , monomer , solid state , intramolecular force , stereochemistry , medicinal chemistry , organic chemistry , receptor , biochemistry , polymer
The set of four triorganotin(IV) diesters of 4‐ketopimelic acid containing {2‐[(CH 3 ) 2 NCH 2 ]C 6 H 4 }‐ as a C,N‐chelating ligand was prepared. Their structures were studied by the help of IR, NMR and X‐ray crystallographic techniques in the case of {{2‐[(CH 3 ) 2 NCH 2 ]C 6 H 4 }SnPh 2 } 2 [(OOCCH 2 CH 2 ) 2 C]. All these compounds are monomeric both in solid state and solution with five‐coordinated tin atoms and medium strong intramolecular SnN connection. The antimycotical activity of these compound was studied and compared with the triorganotin(IV) derivatives of 4‐ketopimelic acid and antimycotical drugs in clinical use. Copyright © 2008 John Wiley & Sons, Ltd.