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Ligand effects in palladium‐catalyzed Suzuki and Heck coupling reactions
Author(s) -
Hanhan M. Emre
Publication year - 2008
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1389
Subject(s) - chemistry , palladium , heck reaction , suzuki reaction , steric effects , diimine , catalysis , imine , ligand (biochemistry) , benzene , medicinal chemistry , polymer chemistry , organic chemistry , biochemistry , receptor
A range of sterically hindered diimine ligands and their palladium (II) complexes were synthesized. These compounds were fully characterized by elemental analysis, 1 H and 13 C‐NMR spectroscopy. The use of the palladium complexes as catalysts for Suzuki and Heck coupling has been studied in an attempt to demonstrate the effect of side groups on catalytic activity. It was clearly seen that the location of side CH 3 groups which bound to benzene ring had little effect on catalytic activity. Interestingly when we changed these CH 3 groups with Cl groups the activity of the complexes increased. On the other hand, side groups which bound to imine nitrogen also had a large effect on catalytic activity. Copyright © 2008 John Wiley & Sons, Ltd.