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New anti‐bacterial polychelates: synthesis, characterization, and anti‐bacterial activities of thiosemicarbazide–formaldehyde resin and its polymer–metal complexes
Author(s) -
Parveen Shadma,
Ahamad Tansir,
Nishat Nahid
Publication year - 2008
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1344
Subject(s) - chemistry , thermogravimetric analysis , formaldehyde , nuclear chemistry , ligand (biochemistry) , metal , metal ions in aqueous solution , polymer , antibacterial activity , polymer chemistry , fourier transform infrared spectroscopy , proton nmr , inorganic chemistry , organic chemistry , bacteria , chemical engineering , biochemistry , receptor , biology , genetics , engineering
New polymeric ligand (resin) was prepared by the condensation of thiosemicarbazides with formaldehyde in the presence of acidic medium. Thisemicarbazide–formaldehyde polymer–metal complexes were prepared with Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) in 1:2 metal:ligand molar ratio. The polymeric ligand and its polymer–metal complexes were characterized by elemental analysis, thermogravimetric analysis (TGA), FTIR, 13 C NMR and 1 H NMR. The geometry of central metal ions was conformed by electronic (UV–vis) and EPR spectra. The antibacterial activities of all the synthesized polymers were investigated against Bacillus subtilis and Staphylococcus aureus (Gram‐positive) and Escherichia coli and Salmonella typhi (Gram‐negative). These compounds showed excellent activities against these bacteria using the shaking flask method. Copyright © 2008 John Wiley & Sons, Ltd.