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Efficient palladium–ferrocenylphosphine catalytic systems for allylic amination of monoterpene derivatives
Author(s) -
Nguyen Duc Hanh,
Urrutigoïty Martine,
Fihri Aziz,
Hierso JeanCyrille,
Meunier Philippe,
Kalck Philippe
Publication year - 2006
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1130
Subject(s) - chemistry , allylic rearrangement , amination , ferrocene , palladium , monoterpene , catalysis , selectivity , reductive amination , organic chemistry , combinatorial chemistry , electrochemistry , electrode
Ferrocenylphosphines added to [Pd(µ‐Cl)(η 3 ‐C 3 H 5 )] 2 dimeric precursor produce efficient catalysts to effect the allylic amination of terpenic allylacetates. Particularly convenient are tetrakis(diphenylphosphino)ferrocene and 1,1′‐bis(diphenylphosphino)ferrocene, which allow the amination of allylacetates with good to excellent selectivity, and have turnover numbers as high as 80 000, for instance, for the formation of allylaniline. Herein, we report on reactions that selectively transform geranylacetate, nerylacetate, linalylacetate and perillylacetate into the corresponding allylic amines. These preparative methods give facile access to various products of great potential industrial interest. Copyright © 2006 John Wiley & Sons, Ltd.