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Synthesis, spectral and biological studies of organotin(IV) complexes of heteroscorpionate
Author(s) -
Joshi Rajkumar,
Sharma Guruaribam Shashikumar,
Kumar Vikrant,
Adil Hashmi Athar,
Kumar Satyendra,
Achila R.,
Ejaz Hussain M.
Publication year - 2006
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/aoc.1114
Subject(s) - chemistry , ligand (biochemistry) , nuclear chemistry , antibacterial activity , stereochemistry , medicinal chemistry , bacteria , biochemistry , receptor , biology , genetics
A heteroscorpionate ligand, potassium hydrobis(benzoato)(salicylaldehyde)borate (KL), has been synthesized. This was converted into organotin complexes R 2 SnL 2 and R 3 SnL complexes by mixing and stirring with a methanolic solution/suspension of organotin chloride. The ligand and its complexes were characterized by elemental analyses and spectral studies (IR, 1 H NMR, 13 C NMR, ESI mass spectra and Thermo gravimetric analysis (TGA)). Antibacterial and antifungal studies of these compounds were evaluated by the disc diffusion method at variable concentration against three species of bacteria ( Staphylococcus aureus, Klebsiella pneumonia and Bacillius subtillis ) and two species of fungi ( Asperjillius fiavus and Candida albicans ). It was found that triorganotin derivatives (R 3 SnL) of the ligand were more effective as compared with diorganotin derivatives (R 2 SnL 2 ). The organotin complexes of borates were tested for their algicidal activity on the cyanobacterial strains Aulosira fertilissma, Anabaena species, Anabaena variabilis and Nostoc muscorum and showed high to moderate toxicity towards the above species. The ligand and its complexes were also tested for its pH effect on soil in vitro for a duration of more than one month and it was found that they are able to kill pests without damaging the soil quality. Copyright © 2006 John Wiley & Sons, Ltd.