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Front Cover: Decoding Protein Gas‐Phase Stability with Alanine Scanning and Collision‐Induced Unfolding Ion Mobility Mass Spectrometry (Analysis & Sensing 1/2021)
Author(s) -
BellamyCarter Jeddidiah,
O'Grady Louisa,
Passmore Munro,
Jenner Matthew,
Oldham Neil J.
Publication year - 2021
Publication title -
analysis and sensing
Language(s) - English
Resource type - Reports
ISSN - 2629-2742
DOI - 10.1002/anse.202000034
Subject(s) - front cover , ion mobility spectrometry , mass spectrometry , gas phase , cover (algebra) , ion , front (military) , chemistry , decoding methods , collision , alanine scanning , analytical chemistry (journal) , alanine , materials science , chromatography , physics , computer science , amino acid , algorithm , biochemistry , engineering , mechanical engineering , computer security , organic chemistry , mutagenesis , meteorology , mutation , gene
The Front Cover shows collision‐induced unfolding (CIU) of an acyl carrier protein in the gas phase as measured by ion mobility spectrometry. The background shows a representation of the alanine scanning mutagenesis used to probe the importance of individual residues in stabilising the compact form of the protein. More information can be found in the Full Paper by J. Bellamy‐Carter, N. J. Oldham, and co‐workers.