Open AccessQuadrupole detection FT‐ICR mass spectrometry offers deep profiling of residue oil: A systematic comparison of 2ω 7 Tesla versus 15 Tesla instruments
Author(s) -
Ge Jinfeng,
Ma Chao,
Qi Yulin,
Wang Xiaowei,
Wang Wei,
Hu Miao,
Hu Qiaozhuan,
Yi YuanBi,
Shi Dejun,
Yue FuJun,
Li SiLiang,
Volmer Dietrich A.
Publication year - 2021
Publication title -
analytical science advances
Language(s) - English
Resource type - Journals
ISSN - 2628-5452
DOI - 10.1002/ansa.202000123
Subject(s) - fourier transform ion cyclotron resonance , mass spectrometry , analytical chemistry (journal) , ion cyclotron resonance , chemistry , nuclear magnetic resonance , cyclotron , ion , physics , chromatography , organic chemistry
Mass resolving power is one of the key features of Fourier transform ion cyclotron resonance mass spectrometry (FT‐ICR MS), which enables the molecular characterization of complex mixtures. Quadrupole (2ω) detection provides a significant step forward in FT‐ICR MS performance, as it doubles the resolving power for a given signal acquisition time. Whether this 2ω detection technique truly substitutes for a higher magnetic field remains unknown however. In this study, a residue oil sample was characterized using both a 2ω 7 Tesla FT‐ICR and a 15 Tesla FT‐ICR instrument, and analytical figures of merit were systematically compared. It was shown that 2ω 7T FT‐ICR MS provided comparable performance in the deep profiling of the complex oil sample, with better signal intensities and reproducibilities for absorption‐mode processing. The 15T FT‐ICR MS gave more precise measurements with better estimates of the sample's elemental compositions. To the best of our knowledge, this is the first published study, which thoroughly compared the performance of 2ω detection on a low magnetic field instrument with that of a high magnetic field FT‐ICR‐MS.