Adherence and its management in clinical trials: Implications for arthritis treatment trials | Zendy

Probstfield Jeffrey L. | Zendy

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Adherence and its management in clinical trials: Implications for arthritis treatment trials

Author(s) -

Probstfield Jeffrey L.

Publication year - 1989

Publication title -

arthritis & rheumatism

Language(s) - English

Resource type - Journals

eISSN - 1529-0131

pISSN - 0004-3591

DOI - 10.1002/anr.1790020314

Subject(s) - clinical trial , medicine , physical therapy , intensive care medicine , intervention (counseling) , arthritis , alternative medicine , disease , pathology , psychiatry

Adherence in clinical trials is a consistent problem regardless of the disease process or organ system under investigation. In this paper data and examples from clinical trials examining cardiovascular diseases are used as the basis for a review of various adherence principles. Issues reviewed include: the importance of adherence in clinical trials, an overall program /or adherence in clinical trials, and specific issues in adherence from arthritis clinical trials. Special attention is given to a program for the prevention of reduced adherence for participants of a clinical trial as well as acute and chronic intervention plans for those with good adherence and those with reduced adherence in a clinical trial.

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