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Back Cover: Enzyme‐like Supramolecular Iridium Catalysis Enabling C−H Bond Borylation of Pyridines with meta ‐Selectivity (Angew. Chem. Int. Ed. 33/2021)
Author(s) -
Trouvé Jonathan,
Zardi Paolo,
AlShehimy Shaymaa,
Roisnel Thierry,
GramageDoria Rafael
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202107624
Subject(s) - iridium , borylation , supramolecular chemistry , pyridine , catalysis , chemistry , selectivity , substrate (aquarium) , cover (algebra) , combinatorial chemistry , organic chemistry , molecule , biology , alkyl , aryl , mechanical engineering , ecology , engineering
Like an enzyme best describes the supramolecular catalyst reported by Rafael Gramage‐Doria et al. in their Research Article on page 18006. The remotely located Zn⋅⋅⋅N interactions within an iridium borylating catalyst are responsible for the unique selectivity and reactivity patterns observed for pyridine C−H bond functionalization. The pyridine approaches the substrate recognition pocket like a Perseid shooting star. Artwork: Romain Baloche.