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On‐Surface Decarboxylation Coupling Facilitated by Lock‐to‐Unlock Variation of Molecules upon the Reaction
Author(s) -
Wang Shaoshan,
Li Zhuo,
Ding Pengcheng,
Mattioli Cristina,
Huang Wujun,
Wang Yang,
Gourdon André,
Sun Ye,
Chen Mingshu,
Kantorovich Lev,
Yang Xueming,
Rosei Federico,
Yu Miao
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202106477
Subject(s) - decarboxylation , steric effects , coupling (piping) , yield (engineering) , molecule , materials science , chemistry , chemical physics , stereochemistry , catalysis , organic chemistry , metallurgy
On‐surface synthesis (OSS) involving relatively high energy barriers remains challenging due to a typical dilemma: firm molecular anchor is required to prevent molecular desorption upon the reaction, whereas sufficient lateral mobility is crucial for subsequent coupling and assembly. By locking the molecular precursors on the substrate then unlocking them during the reaction, we present a strategy to address this challenge. High‐yield synthesis based on well‐defined decarboxylation, intermediate transition, and hexamerization is demonstrated, resulting in an extended and ordered network exclusively composed of the newly synthesized macrocyclic compound. Thanks to the steric hindrance of its maleimide group, we attain a preferential selection of the coupling. This work unlocks a promising path to enrich the reaction types and improve the coupling selectivity hence the structual homogeneity of the final product for OSS.