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Inside Cover: Implications of Quenching‐to‐Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye‐Labeled Nanoparticles (Angew. Chem. Int. Ed. 28/2021)
Author(s) -
Yang Guangze,
Liu Yun,
Hui Yue,
Chen Dong,
Weitz David A.,
Zhao ChunXia
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202105984
Subject(s) - biodistribution , chemistry , quenching (fluorescence) , nanoparticle , fluorescence , biophysics , molecule , nanotechnology , materials science , organic chemistry , biochemistry , physics , quantum mechanics , in vitro , biology
A quenching‐to‐dequenching switch of fluorescence‐labeled nanoparticles in biological environments is unveiled by Chun‐Xia Zhao and co‐workers in their Research Article on page 15426. With dye molecules in a solid state, the release and/or degradation of the dye‐labeled nanoparticles in biological environments led to a several‐fold increase in fluorescence intensity due to the state switch, which has significant implications in quantitative cell uptake and biodistribution studies.