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Cover Picture: Liposomes as Carriers of Membrane‐Associated Proteins and Peptides for Mass Spectrometric Analysis (Angew. Chem. Int. Ed. 20/2021)
Author(s) -
Frick Melissa,
Schwieger Christian,
Schmidt Carla
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202103931
Subject(s) - liposome , chemistry , mass spectrometry , membrane protein , biophysics , membrane , chromatography , biochemistry , biology
Liposomes as carriers of proteins and peptides enable investigation of lipid clusters, protein oligomers and protein–lipid interactions in mass spectrometric analysis. In their Research Article on page 11523, Carla Schmidt et al. show that proteoliposomes dissociate in the gas phase of a mass spectrometer, releasing associated proteins or peptides. This new approach shows that liposomes can be used to study proteins and peptides as well as their interactions with lipids.