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Inside Back Cover: Aptamer Blocking Strategy Inhibits SARS‐CoV‐2 Virus Infection (Angew. Chem. Int. Ed. 18/2021)
Author(s) -
Sun Miao,
Liu Siwen,
Wei Xinyu,
Wan Shuang,
Huang Mengjiao,
Song Ting,
Lu Yao,
Weng Xiaonan,
Lin Zhu,
Chen Honglin,
Song Yanling,
Yang Chaoyong
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202103676
Subject(s) - aptamer , blocking (statistics) , virus , virology , int , cover (algebra) , covid-19 , viral entry , receptor , chemistry , biology , microbiology and biotechnology , medicine , biochemistry , viral replication , computer science , mechanical engineering , disease , pathology , infectious disease (medical specialty) , engineering , operating system , computer network
An aptamer blocking strategy is developed by Honglin Chen, Yanling Song, Chaoyong Yang, and co‐workers in their Research Article on page 10266 to inhibit SARS‐CoV‐2 infection. An aptamer probe was engineered to bind to the spike protein of SARS‐CoV‐2, which inhibits infection with the virus by blocking the interaction of the virus with ACE2 receptors on the human cell membrane.