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Inside Cover: Interplay between a Foldamer Helix and a Macrocycle in a Foldarotaxane Architecture (Angew. Chem. Int. Ed. 15/2021)
Author(s) -
Gauthier Maxime,
Koehler Victor,
Clavel Caroline,
Kauffmann Brice,
Huc Ivan,
Ferrand Yann,
Coutrot Frédéric
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202102302
Subject(s) - foldamer , helix (gastropod) , cover (algebra) , axle , stereochemistry , crystallography , chemistry , engineering , biology , paleontology , mechanical engineering , snail
A foldarotaxane molecular architecture is reported by Yann Ferrand, Frédéric Coutrot et al. in their Communication on page 8380. It comprises a molecular axle encircled by a macrocycle and wrapped with a foldamer helix. Through its controlled localization, the macrocycle alters the association between the helix and the axle, while the helix compartmentalizes the molecular shuttle. In the picture and X‐ray structure, the snake wraps itself around the tree branch and pushes that way the bulky surrounding wheel.