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Frontispiece: Key Intermediate Species Reveal the Copper(II)‐Exchange Pathway in Biorelevant ATCUN/NTS Complexes
Author(s) -
Kotuniak Radosław,
Strampraad Marc J. F.,
BossakAhmad Karolina,
Wawrzyniak Urszula E.,
Ufnalska Iwona,
Hagedoorn PeterLeon,
Bal Wojciech
Publication year - 2020
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202082861
Subject(s) - bioinorganic chemistry , chemistry , copper , extracellular , redox , stereochemistry , biochemistry , combinatorial chemistry , inorganic chemistry , organic chemistry
Bioinorganic Chemistry W. Bal et al. demonstrate in their Communication on page 11234 that Cu II binding to GGH peptide proceeds via partially coordinated species. A 2N‐coordinated species with Cu II /Cu I redox activity is the long‐sought reactive intermediate for extracellular copper delivery.